Lyoprotectant yog dab tsi?

Hauv cov dej khov ua kua dej qhuav, ntxiv nrog rau cov neeg ua haujlwm, cov tshuaj lom los yog tshuaj kho mob zoo, lawv tau hu ua lyoprotectants. Nws yog txawv ntawm qhov adjuvant, adjuvant muaj ib tug kho cov nyhuv, thiab tus neeg sawv cev kev tiv thaiv tsis muaj kev kho mob zoo.

Qee cov khoom ua kua tau lyophilized nyias, tab sis qee cov khoom ua kua feem ntau tsis yooj yim lyophilized. Thiaj li yuav ua rau qee cov khoom yuav tsum tau lyophilized ntse, kev txhim kho thiab stability ntawm cov khoom lyophilized yuav zoo tuaj, los yog cov khoom lyophilized yuav ua zoo nkauj, thiab qee yam tshuaj ntxiv yuav tsum tau ntxiv rau cov khoom, uas yog cov neeg sawv cev tiv thaiv, qee zaus hu ua kev tiv thaiv. Tus neeg sawv cev yog tus ncua sij hawm ncua, ib qho muab tub lim, ib qho khoom plig, ib ntu, ib lub hauv paus, thiab cov zoo li. Cov tiv thaiv yog chiv tsis zoo thiab tsis tuaj yeem nrog cov khoom lyophilized.

Lub luag haujlwm ntawm cov neeg sawv cev tiv thaiv:

1. Cov kab mob thiab kab mob yuav tsum loj hlob raws li tej kab lis kev cai, tab sis qee qhov kev cai kab lis kev cai feem ntau nyuaj rau cais tawm ntawm cov kab mob thiab kab mob, thiab lawv feem ntau tau khov-qhuav ntawm cov kab lis kev cai kab lis kev cai. Piv txwv, broth, skim, protein, thiab lwm yam.

2. Qee cov tshuaj ua muaj kuab tsawg heev thiab muaj tsawg heev qhuav. Cov khoom uas tau qhuav thaum lub sij hawm lyophilization yog ntws tawm los ntawm cov roj sublimated. Nyob rau hauv thiaj li yuav txhim kho lub concentration thiab nce lub qhuav teeb meem cov ntsiab lus, lub lyophilized khoom muaj peev xwm tsim ib tug zoo agglomerate. Yog li, nws yog ib qho tsim nyog ntxiv rau ib tug tub lim nyuj xws li tias qhov concentration ntawm qhov teeb meem muaj teeb meem yog nruab nrab ntawm 4 thiab 25%. Cov pob ntim lossis cov khoom ntim yog: sucrose, lactose defatting, protein thiab hydrolyzate, polyvinylpyrrolidone, dextran, sorbitol, thiab cov zoo li.

3. Qee yam tshuaj yeeb dej caw tshwj xeeb yog khaus thiab yuav ua rau lub cev los yog tshuaj muaj zog thaum lub sij hawm khov thiab ziab khaub ncaws. Yog li, qee cov neeg ua haujlwm tiv thaiv lossis cov tshuaj tiv thaiv antifreeze ntxiv rau txo kev puas tsuaj hauv kev khov thiab ziab khaub ncaws. Piv txwv, dimethyl hydrazine, glycerin, dextran (dextran), saccharides, polyvinylpyrrolidone, thiab cov zoo li ntxiv.