Qhov sib txawv ntawm khov drying thiab zoo tib yam ziab

Kev ziab kom qhuav thiab ziab zoo tib yam muaj qhov sib txawv tseem ceeb hauv cov qauv, txheej txheem thiab kev siv.

Qhov txawv ntawm txoj cai
Kev ziab kom qhuav: Nws yog txoj kev ziab kom qhuav ntawm qhov kub thiab txias, feem ntau qis dua 0 degree, rau lub hom phiaj ntawm kev khaws cov khoom. Nws tshem tawm cov dej noo los ntawm qhov ua ntej khov cov khoom kom qhuav rau hauv cov khoom, thiab tom qab ntawd vaporizing cov dej noo hauv nws los ntawm sublimation nyob rau hauv lub tshuab nqus tsev. Cov txheej txheem no yuav tsis cuam tshuam rau lub xeev agglomeration ntawm cov khoom, yog li cov khoom qub tuaj yeem khaws cia kom ruaj khov thiab tsis raug compressed thiab agglomerated.

Ordinary drying: suav nrog lub hnub ziab, ziab kom qhuav, qhov cub kom qhuav, tshuaj tsuag kom qhuav thiab lub tshuab nqus tsev, thiab lwm yam. Cov txheej txheem no feem ntau ua rau kub siab tshaj 0 degree lossis siab dua. Lawv evaporate dej los ntawm cua sov, tab sis vim yog qhov kub thiab txias, qee cov khoom tsis haum hauv cov khoom yuav ploj mus, thiab qee cov khoom kub-rhiab yuav raug denatured lossis deactivated.

Qhov txawv ntawm cov txheej txheem
Kev ziab kom qhuav: Thaum lub sij hawm khov-qhuav, cov dej noo hauv cov khoom yog thawj zaug khov rau hauv cov dej khov, thiab tom qab ntawd nyob rau hauv lub tshuab nqus tsev, cov dej khov nab kuab ncaj qha sublimate rau hauv dej vapor, yog li ua tiav lub hom phiaj ntawm ziab. Cov txheej txheem no tuaj yeem ua tiav ntawm qhov kub qis, feem ntau tsis tshaj 40 degree.

Ordinary drying: Hauv kev ziab ib txwm, cov dej hauv cov khoom yog evaporated los ntawm cua sov, thiab cov dej vapor yog tom qab ntawd nqa tawm los ntawm huab cua los yog lwm txoj kev. Cov txheej txheem no feem ntau yuav tsum tau kub siab dua thiab yuav ua rau muaj kev hloov pauv ntawm cov xim, cov duab, thiab kev ntxhib los mos ntawm cov khoom.

Qhov sib txawv ntawm daim ntawv thov
Freeze-drying: dav siv hauv kev lag luam chemistry, kev lag luam tshuaj, kev lag luam zaub mov thiab kev tshawb fawb tshawb fawb, tshwj xeeb tshaj yog nyob rau hauv biopharmaceuticals uas muaj cov tshuaj lom neeg lom neeg. Nws yog qhov tsim nyog rau kev ua cov tshuaj uas yooj yim deteriorate los yog poob kev ua haujlwm ntawm qhov kub thiab txias.
Kev ziab khaub ncaws dav dav: haum rau ntau hom tshuaj, nrog rau cov khoom noj, tshuaj, khoom siv tshuaj, thiab lwm yam. Nws yog ntau yam kev ziab kom qhuav tab sis yuav raug txwv thaum ua haujlwm nrog qee cov ntaub ntawv kub-rhiab.

Qhov zoo sib piv
Freeze drying:
Ntau cov khoom kub-rhiab heev tsis dhau denaturation lossis inactivation.
Thaum ziab ntawm qhov kub qis, qee cov khoom tsis haum rau hauv cov khoom poob qis heev.
Thaum lub sij hawm khov-drying txheej txheem, kev loj hlob ntawm cov kab mob thiab kev ua ntawm cov enzymes tsis tuaj yeem mus, yog li cov khoom qub tuaj yeem khaws cia.

Txij li thaum nws qhuav nyob rau hauv lub xeev khov, lub ntim yuav luag tsis hloov, tus qauv qub yog khaws cia, thiab tsis muaj concentration tshwm sim.
Txij li cov dej noo nyob rau hauv cov khoom muaj nyob rau hauv daim ntawv ntawm cov dej khov muaju tom qab pre-freezing, cov yaj inorganic ntsev uas yog yaj nyob rau hauv dej yog sib npaug zos rau cov khoom. Thaum lub sij hawm sublimation, cov khoom yaj yaj yaj hauv dej yog precipitated, uas zam qhov tshwm sim ntawm qhov tawv tawv los ntawm nag lossis daus ntawm inorganic ntsev nqa los ntawm sab hauv cov dej noo ntawm cov khoom txav mus rau saum npoo hauv txoj kev ziab dav dav.

Kev ziab kom qhuav:
Cov cuab yeej siv tau yooj yim thiab yooj yim rau kev khiav lag luam.
Nws muaj ntau yam kev siv thiab tuaj yeem ua ntau hom tshuaj.
Lub tshuab ziab khaub ncaws yog ceev thiab efficiency siab.
Kev ziab kom qhuav thiab ua kom qhuav zoo tib yam txhua tus muaj lawv tus kheej cov yam ntxwv thiab kev ua haujlwm ntawm daim ntawv thov. Kev xaiv ntawm txoj kev ziab yog nyob ntawm cov khoom tshwj xeeb thiab lub hom phiaj ziab.